Harmony analyzes DNA
During pregnancy, the mother's blood contains fragments of the developing baby’s DNA. Harmony is a new type of test that analyzes this DNA in a blood sample to predict the risk of Down syndrome (trisomy 21), as well as trisomies 18 and 13, in the pregnancy.
A targeted approach
While traditional blood tests can miss as many as 15% of Down syndrome cases in pregnant women2, Harmony’s DNA-based technology accurately identifies more than 99% of cases1.
The Harmony Prenatal Test specifically targets the DNA in chromosomes 21, 18 and 13. While rare, these are the most common trisomies that occur in babies born to women of any age, when no other risk factors are known. 4
Superior quality control
The Harmony Prenatal Test incorporates extensive quality controls. These controls include measurement of the amount of the developing baby’s DNA in each sample, to ensure that there is enough DNA present to return a reliable result.3 While it may seem surprising, not all DNA-based genetic tests take the care to measure this basic information.
Norton et al. N Engl J Med. 2015 Apr 23;372(17):1589-97
ACOG Practice Bulletin 77. ACOG Committee on Practice Bulletins. Obstet Gynecol. 2007 Jan;109(1):217-27
Sparks et al. Am J Obstet Gynecol. 2012 Apr;206(4):319.e1-9.
Grati FR et al. Am J Med Genet Part A 152A:1434–1442.