FAQs for expecting parents

  • How accurate is the Harmony Prenatal Test?

    Harmony’s DNA-based technology correctly identifies Down syndrome in more than 99% of cases. By comparison, traditional blood tests can miss as many as 15% of Down syndrome cases in pregnant women.

    Harmony is also much less likely than traditional tests to give you a false-positive result, meaning there is much less chance your doctor would recommend follow-up invasive testing, such as amniocentesis.

    Read more about the accuracy of Harmony.

  • How does the Harmony test work?

    When you are pregnant, your blood contains fragments of your developing baby’s DNA. Harmony Prenatal Test is a new type of test that analyzes DNA in a sample of your blood to predict the risk of Down syndrome (trisomy 21) and other genetic conditions called trisomy 18 and trisomy 13.

    Read more about the Technology behind Harmony.

  • How is the Harmony test different from other blood tests for Down syndrome?

    Harmony delivers clear answers as early as the first trimester with a single blood draw. Other commonly used tests for Down syndrome are performed later in pregnancy and require multiple office visits. Traditional 1st trimester serum screening tests are associated with a false-positive rate as high as 5%. 
    Harmony uses a unique method of targeted DNA analysis that, combined with extensive quality controls, achieves over 99% accuracy and a false-positive rate less than 0.1%.

    Read more about the Technology behind Harmony.

  • Can the Harmony test also evaluate the X and Y sex chromosomes?

    Yes, Harmony Prenatal Test includes the option to evaluate the number of X and Y sex chromosomes, if you ask your doctor to request this additional analysis.

  • Should I take the Harmony test if I am under 35?

    The risk of Down syndrome in a pregnancy increases with maternal age, however, most cases occur in women who are under age 35. Harmony, a new type of DNA-based blood test, has been extensively validated in women both over and under 35.

  • When can I take the Harmony test?

    You can get the Harmony test with a simple blood draw as early as 10 weeks into your pregnancy, or any time later in pregnancy. 

  • How long does the Harmony test take?

    Harmony is a simple blood test, so it only takes a couple of minutes at your healthcare provider’s office.

    In seven days or less, your healthcare provider will receive the results and can share them with you.

     

    Read more about Taking the Test.

  • How much does Harmony Prenatal Test cost?

    Harmony is covered by many insurance plans. While the exact cost depends on your insurance coverage, Harmony provides insured parents with a program that allows them to pay no more than a maximum out-of-pocket. If you do not have health insurance, or have financial need, there are additional Harmony programs in the US that can assist with test costs.

    Learn more about Harmony Access Programs.

    Or call 855-927-4672 for help with billing or payment questions.

  • Where can I find out more about Down syndrome, trisomy 18 and trisomy 13?

    In the Resources section, you will find a list of Advocacy and Support Groups with links to organizations that support families and individuals affected by trisomies and provide information about these conditions to the public.
  • I’m expecting twins. Can I get the Harmony Prenatal Test?

    Yes. Harmony can be used in twin pregnancies.

  • I’m expecting a baby through IVF. Can I get the Harmony test?

    Yes. In most cases, the Harmony test can be used in pregnancies conceived through in vitro fertilization (IVF).

  • I have another question that is not answered here. Who do I ask?

    For questions that relate to your specific case and personal concerns, it’s best to talk to your healthcare provider. A list of Questions for your healthcare provider you can print for your next visit is available.

    If you have other questions about the Harmony test, you can speak to one of our Patient Advocacy Representatives. They are available to help you and give you more information. Call 1-855-9-ARIOSA (855-927-4672) to speak to one of them. Outside of U.S. call +1 925-854-6246.

    This line is open Monday through Friday from 9am to 7pm EST, except major holidays.

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