A new, DNA-based technology
When you are pregnant, your blood contains fragments of your baby’s DNA.
Harmony Prenatal Test is a new type of test that analyzes DNA in a sample of your blood to predict the risk of Down syndrome (trisomy 21) and certain other genetic conditions.
As early as 10 weeks
Harmony Prenatal Test requires a single blood draw. It can be done as early as 10 weeks or later in pregnancy.
Other commonly used tests for Down syndrome are performed later in pregnancy and may require multiple office visits.
A more accurate test
The Harmony Prenatal Test is a screening test that is more accurate than traditional Down syndrome blood tests.1 The Harmony test is much less likely to give a false-positive result compared to traditional tests such as the first trimester screening test.1 That means there will be much less chance your doctor would recommend follow-up diagnostic testing, such as amniocentesis.2
Harmony also tests for two other genetic conditions, trisomy 18 (Edward syndrome) and trisomy 13 (Patau syndrome).
In addition, with Harmony you have the option to evaluate fetal sex, X and Y sex chromosomes.
Non-invasive prenatal testing based on cell-free DNA analysis is not considered diagnostic. Once you have your Harmony test results, you can discuss your pregnancy care with your healthcare provider.
|False Positive Rate*||Detection Rate**|
|Harmony Prenatal Test||Less than 1 in 1,600||More than 99 in 100|
|Traditional Test***||1 in 20||79 in 100|
Data Source: Norton et al. N Engl J Med. 2015 Apr 23;372(17):1589-97
*Reports a high risk for Down syndrome when it is NOT actually present
**Correctly indicates a high risk for Down syndrome when it IS present
***Serum Papp-A, total or free B-hCG & Nuchal Translucency
- Norton et al. N Engl J Med. 2015 Apr 23;372(17):1589-97
- Wax et al. J Clin Ultrasound 2015 Jan; 43(1):1-6.